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Altogether, the findings identified key aging-related differentially expressed genes in multiple cell types that may underly the phenotype of hippocampal aging, characterized by increased heterochromatin erosion, genomic instability, cytosolic Amyloid-beta aggregation, inflammation and senescence and decreased neurogenesis
Arnold and Chen, 2009), epigenetic (Sase et al., 2019), and mitochondrial functions (Biala et al., 2011) that differ between the sexes
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