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KEY FINDINGS In an eight-week randomized, double-blind, placebo-controlled trial involving 50 adults seeking treatment for moderate-to-severe AUD, participants receiving oral semaglutide showed: Fewer heavy drinking days Reduced alcohol consumption per drinking occasion Lower day-to-day alcohol cravings Fewer alcohol-related problems Improved overall drinking risk level Reduced cannabis use days While not all measures changed in controlled laboratory settings, the overall pattern showed consistent reductions in harmful real-world drinking behavior
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Most GLP-1 users should aim for 810 glasses of water daily, but individual hydration needs depend on dose, gastric effects, and kidney function
You Sleep Better: Quality sleep is a non-negotiable cornerstone of metabolic health
the formal RCT is still pending
Beginners should start at 20-30 mcg daily for 4 weeks to assess tolerance, while experienced users may use 40-50 mcg split into two daily doses for 4-6 weeks maximum
