it won't, of course, be alone in your lists
For example, Marvel Super Heroes Collector Boosters can contain cards from the main set, the bonus sheet, the Commander precons, the Jumpstart Boosters, and the Scene Boxes
Omniscience was very scary in game 1, but became totally manageable after sideboarding
I might worry a little about the four pips, but white is the primary color in the deck
You might not have an urgent need for a specific card on turns 2-4, so rather than potentially wasting a tutor on a card that could be rendered useless as the game develops, you can simply set yourself up to make a more informed decision later